Handbook of Chiral Chemicals - 2nd Edition

Name: Handbook of Chiral Chemicals - 2nd Edition
Brand: CRC Press

CRC Press

This book discusses various aspects of chiral fine chemicals including their synthesis and uses at scale. It also discusses how the key subclasses of the chiral pool are obtained and covers methods that can be used to introduce or control stereogenic centers. > \nAs pharmaceutical companies look to develop single enantiomers as drug candidates, chemists are increasingly faced with the problems associated with this subclass of organic synthesis. \""The Handbook of Chiral Chemicals, Second Edition\"" highlights the problems associated with the production of chiral compounds on a commercial scale. The handbook first elaborates upon starting materials obtained from a 'chiral pool', which can be derived from natural products. Then it explains methods and reactions that can introduce or influence stereogenic centers, particularly asymmetric hydrogenations, oxidations, pericyclic reactions, and enzymatic methods.While hydrogenations have been the most widely employed approach for the larges