Formulation and Analytical Development for Low-Dose Oral Drug... - 9780470056097

Formulation and Analytical Development for Low-Dose Oral Drug Products\n\nJack Zheng (Edited by), JY Zheng (Author)\n\n9780470056097, Wiley\n\nHardback, published 10 March 2009\n\n500 pages\n24.3 x 16.3 x 2.8 cm, 0.798 kg\n\nThere are unique challenges in the formulation, manufacture, analytical chemistry, and regulatory requirements of low-dose drugs. This book provides an overview of this specialized field and combines formulation, analytical, and regulatory aspects of low-dose development into a single reference book. It describes analytical methodologies like dissolution testing, solid state NMR, Raman microscopy, and LC-MS and presents manufacturing techniques such as granulation, compaction, and compression. Complete with case studies and a discussion of regulatory requirements, this is a core reference for pharmaceutical scientists, regulators, and graduate students.\n\nPreface xv \nForeword xix \nContributors xxi \n1 An Overview 1\nJack Y. Zheng \n1.1 The Drug Discovery and D]