Computational Biochemistry and Biophysics by Oren M. Becker, ... - 9780367397579

Computational Biochemistry and BiophysicsAuthor(s): Oren M. Becker, Alexander D. MacKerell Jr., Benoit Roux, Masakatsu Watanabe\nFormat: Paperback\nPublisher: Taylor & Francis Ltd, United Kingdom\nImprint: CRC Press\nISBN-13: 9780367397579, 978-0367397579\nSynopsis\nCovering theoretical methods and computational techniques in biomolecular research, this book focuses on approaches for the treatment of macromolecules, including proteins, nucleic acids, and bilayer membranes. It uses concepts in free energy calculations, conformational analysis, reaction rates, and transition pathways to calculate and interpret biomolecular properties gleaned from computer-generated membrane simulations. It also demonstrates comparative protein structure modeling, outlines computer-aided drug design, discusses Bayesian statistics in molecular and structural biology, and examines the RISM-SCF/MCSCF approach to chemical processes in solution.